Alliance Clinical Network

History of GLP-1 Approvals in the U.S.

The following table provides a brief history of GLP-1 therapies that have received FDA regulatory approval. In addition to identifying brand name, manufacturer and launch date, the chart shows whether the product received regulatory approval for weight loss or diabetes indications.  

Brand Name Generic Name Sponsor / Manufacturer Indication Launch Date
Byetta
exenatide
AstraZeneca
Diabetes
4/28/05
Victoza
liraglutide
Novo Nordisk
Diabetes
1/25/10
Bydureon
exenatide
AstraZeneca
Diabetes
1/27/12
Tanzeum
albiglutide
GSK
Diabetes
4/15/16
Trulicity
dulaglutide
Eli Lilly
Diabetes
9/18/24
Saxenda
liraglutide
Novo Nordisk
Weight Loss
12/23/14
Adlyxin
lixisenatide
Sanofi
Diabetes
7/27/20
Bydureon
Bcise
exenatide
AstraZeneca
Diabetes
10/20/17
Ozempic
semaglutide
Novo Nordisk
Diabetes
12/15/17
Rybelsus
semaglutide
Novo Nordisk
Diabetes
(oral formulation)
1/16/20
Wegovy
semaglutide
Novo Nordisk
Weight Loss
6/4/21
Mounjaro
tirzepatide
Eli Lilly
Diabetes
5/13/22
Zepbound
tirzepatide
Eli Lilly
Weight Loss
11/8/23

*Products shaded in grey are no longer on the market.

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